Abdominal pain - Acute 1  FBE, EUC, LFT, Amylase, Lipase, CRP, pregnancy test

Abdominal pain - Acute 2 C1 inhibitor level, C3, C4, PGB spot urine

Abdominal pain - Chronic 1 CRP, EUC, LFT, FBE, Gliadin Abs IgG, Gliadin Abs IgM, Iron studies, Lipase, TTG Abs IgA

Acromegaly 1 - Growth hormone, GGT measuring GH + glucose, IGF-1

Addison's disease 1 - ACTH, Calcium, Cortisone 0800, EUC, LFT, fasting glucose, Renin, short synacthen test, TSH(+/- FT4 if TSH abnormal)

Alopecia 1 - ANA (+ ds DNA quant if detected), ENA, iron studies, TSH(+/- FT4 if TSH abnormal)

Amenorrhoea - Primary 1 FSH, LH, BHCG, Progresterone, Prolactin, TFT

Amenorrhoea - Primary 2 Androstenedione, chromosome cytogenetics, DHEAS, FSH, LH, Oestradiol, SHBG, Testosterone

Amenorrhoea - Secondary, no hirsutism 1 17-PH progresterone, Androstenedione, chromosome cytogenetics, DHEAS, FSH, BHCG, LH, Oestradiol, SHBG, Testosterone, TFT

Amenorrhoea - Secondary, with hirsutism 1 17-PH progresterone, Androstenedione, DHEAS, FSH, BHCG, LH, Oestradiol, Prolactin, SHBG, Testosterone, TFT

Anaemia 1 - Vit B12, folate, iron studies, reticulocyte count, FBE

Anaemia, Macrocytic/Pernicious 1 - EUC, LFT, FBE, Folate, Reticulocyte count, Vit B12

Anaemia, Macrocytic/Pernicious 2 - FBE, Folate, Fasting gastrin, Intrinsic factor Abs, Parietal cell Abs, TSH(+/- FT4 if TSH abnormal)

Anaemia Microcytic 1 - EUC, LFT, ESR, FBE, iron studies, FOBT, Reticulocyte

Anaemia Microcytic 2 - MCS, stool MCS, Faecal multiplex PCR, Hb electrophoresis, iron studies, FOBT

Anaemia Normocytic 1 - EUC, LFT, iron studies, Reticulocyte count, TSH(+/- FT4 if TSH abnormal)

Anaemia Normocytic 2 - ANA , Coombs direct, ENA, folate, FBE, Haptoglobin, Hb electrophoresis, Vit B12

Antenatal 1^st visit 1 - Blood group and antibodies, FBE, EUC, LFT, iron studies, glucose, HbA1c, TSH, Calcium, Mg, Phosphate, Vit D, Vit B12, folate, BHCG, HBsAg, anti-Hbc, anti-HBs, Hep C serology, HIV, Urine MCS, Rubella serology, Syphillis serology, Chickenpox serology, Urine MCS, Urine Chlamydial and gonorrhoeal PCR

Antenatal 1^st visit 2 - Urine gonorrhoeal and Chlamydial PCR, iron studies, glucose, Hb electrophoresis, TSH(+/- FT4 if TSH abnormal), Vit D

Antenatal 26W to 28W visit 1 - Blood group and antibodies, FBE, GGT

Antenatal 35W to 37W visit 1 - Group B strep vaginal swab

Antenatal First Trimester screen (9W to 13W 6D) - BHCG, PAPP-A

Antenatal pre-pregnancy 1- Rubella serology, TSH(+/- FT4 if TSH abnormal), Chickenpox serology

Antenatal Second Trimester screen (14W to 20W) - AFP, BHCG, Unconjugated oestriol

Arthritis Infectious Cause Dx 1 - Barmah Forest serology, Parvovirus serology, Ross River serology, Rubella serology

Arthritis Rheumatoid Dx 1 - anti CCP Abs, ANA, CRP, ESR, FBE, LFT, EUC, uric acid, Calcium, Phosphate, Rheumatoid factor, anti-glutamic acid decarboxylase antibodies, anti-acetylcholine antibodies, CK

Ascites 1 - EUC, LFT, Ascitis fluid analysis

Autoimmune Antiphospholipid 1 - APTT, Cardiolipin Abs, Lupus anticoagulant, INR, Beta2 glycoprotein 1 Abs

Autoimmune Scleroderma 1 - ANA, CCP Abs, ENA, Rheumatoid factor

Autoimmune Sjogren Syndrome 1 - Rheumatoid factor, ANA, ENA, FBE, EUC

Autoimmune Sjogren Syndrome 2 - CCP Abs, CRP, ESR, Immunofixation + Electrophoresis, Protein electrophoresis

Autoimmune Systemic Lupus 1 - ANA, dsDNA, ENA, ESR, FBE, EUC

Autoimmune Systemic Lupus 2 - ANCA, Cardiolipin Abs, Chromatin Abs, C3, C4, Beta 2 glycoprotein 1 Abs, Urine MCS

Autoimmune Vasculitis 1 - ANA, ANCA, CRP, ESR, FBE, EUC, LFT

Autoimmune Vasculitis 2 - ANCA, Cardiolipin Abs, Cryoglobulins, GBMA, Beta 2 glycoprotein 1 Abs

Back Pain 1 - CRP, ESR, FBE, EUC, LFT

Back Pain 2 - Calcium, Free light chains, HLA B27, Immunofixation + Electrophoresis, Protein electrophoresis, urine electrophoresis, Rheumatoid factor, Vit D

Bariatric surgery (Presurgical screening) - FBE, EUC, LFT, Calcium, Mg, Phosphate, Vit B12, folate, iron studies, TSH, PTH, Vit D, HbA1c, Serum insulin, glucose, fasting lipids, LDL, HDL, Thiamine, Zn Vit A, E, K, Copper, uric acid

Bariatric surgery (Postsurgical screening) - FBE, EUC, LFT, Calcium, Mg, Phosphate, PTH, Vit D, TSH, iron studies, Thiamine, Vit B12, folate, Zn, Vit A, D, E, K (RYGB or BPD/DS), Copper (RYGB or BPD/DS), Selenium (BPD/DS)   
Roux-en-Y gastric bypass (RYBG), Biliopancreatic diversion with duodenal switch(BPD/DS)

Cardiovasc disease long term risk 1 - EUC, LFT, fasting glucose, fasting lipids, LDL, HDL, urine microalbumin

Cardiovasc disease short term risk 1 - BNP, CRP high sensitvitiy, troponin

Cardiovasc chest pain - troponin, FBE

Cardiovasc CHF 1 - FBE, BNP, EUC, LFT, urine microalbumin, Urine MCS

Cardiovasc CHF 2 - glucose, fasting lipids, LDL, HDL, iron studies, TSH(+/- FT4 if TSH abnormal)

Cardiovasc palpitations - TSH(+/- FT4 if TSH abnormal), EUC, LFT

Choleastasis 1 - Amylase, LFT, Lipase

Cirrhosis Assessment 1 - AFP, ANA, EUC, LFT, FBE, INR

Cirrhosis autoimmune 1 - ANA, mitocondrial Abs, smooth muscle Abs

Cirrhosis Dx 1 - Alpha 1 antitrypsin, Ceruloplasmin, CDT, Copper, HBsAg, anti-HBc, anti-HBs, Hepatitis C serology, iron studies, LFT

Coeliac Disease - patient with family history - HLA-DQ2, HLA-DQ8

Coeliac Disease 1 - Endomysial Abs, Gliadin Abs, Ig A, TTG Abs

Conjunctivitis 1 - Adenovirus PCR swab, Chlamydial PCR, Herpes Simplex PCR, RAST, Varicella Zoster PCR

Cough Syndrome 1 - RAST, Pertussis PCR, ESR, Atypical bacterial serology, Sputum MCS

Cough Syndome 2- Throat swab Covid 19 PCR, Influenza PCR, Pertussis PCR

Cushing's Syndrome - ACTH, 24 hour urine cortisol, Cortisol- midnight salivary, Dexamethasone suppression - overnight, EUC, LFT, fasting glucose

Delayed development female 1 - LH, Oestradiol

Delayed development male 1 - LH, Testosterone

Depression 1 -  EUC, LFT, fasting glucose, TSH(+/- FT4 if TSH abnormal), Vit B12

Depression 2 - Dexamethasone suppression - overnight, urine drug screen, folate, FBE

Diabetes insipidus 1 - fasting glucose, osmolality, EUC

Diabetes insipidus 2 - Osmolality H₂O deprivation test

Diabetes 3 monthly management 1 - EUC, LFT, HbA1c, fasting lipids, LDL, HDL

Diabetes annual management 1 - EUC, LFT, HbA1c, fasting lipids, LDL, HDL, urine microalbumin, TSH(+/- FT4 if TSH abnormal)

Diabetes juvenile Dx1 - fasting glucose, EUC, LFT

Diabetes juvenile Dx2 - GAD Abs, IA-2 Abs, Insulin Abs, Islet cell Abs

Diabetes NIDDM Dx1 - EUC, LFT, fasting glucose, HbA1c, fasting lipids, LDL, HDL, urine microalbumin

Dialysis 1 - EUC, LFT, FBE, Calcium, Albumin, Phosphate, Magnesium, PTH

Diarrhoea 1 - Faeces Adenovirus, MCS, parasite, Rotavirus

Diarrhoea 2 - Faces C.difficile detection, Norovirus, Reducing substances

Diarrhoea 3 - 24 hour urine catecholamines, Gliadin Abs, TTG Abs, Vasoactive Intestinal Peptide

Eosinophilia 1 - FBE, IgE, Lymphocyte markers, Stool MCS, parasites, RAST

Eosinophilia 2 - Filiariasis serology, Schistosoma serology, Stronglyloides serology, Urine Schistosomes

Fatigue 1 - EUC, LFT, FBE, fasting glucose, TSH(+/- FT4 if TSH abnormal)

Fatigue 2 - Barmah Forest serology, CMV serology, EBV serology, iron studies, Ross River serology

Fatigue 3 - ANA, ENA, Immunofixation + Electrophoresis, Protein electrophoresis

Genital ulcer 1 - Herpes Simplex PCR swab, HIV, Swab MCS, Syphillis serology, Varicella Zoster PCR swab

Goitre 1 - Urine iodine, TFT, Thyroid antibodies

Gout 1 - EUC, LFT, FBE, Urate, Joint Aspirate MCS

Graves' disease  - TFT, Thyroid antibodies, TSH receptor Abs

Hepatitis Acute unknown origin 1 - HBsAg, anti-HBc, anti-HBs, Hepatitis C serology, anti mitochondrial antibodies, anti smooth muscle antibodies, ANA, Ceruloplasmin level, Alpha 1 antitrypsin, Coeliac serology, CMV, EBV serology

Hepatitis Acute unknown origin 2 - CMV serology, EBV serology, Hepatitis E serology

Hepatitis Chronic B - Hep B c Ab, Hep B s Ag, viral load

Hepatitis Chronic C - Hepatitis C serology, Hepatitis C RNA

Hepatitis Chronic Unknown 1 - HBsAg, anti-HBc, anti-HBs, Hepatitis C serology, ANA, Mitochondrial Abs, Smooth muscle Abs

Hepatitis immunity status - Hep B s Ab, Hep A Ig

Hepatomegaly 1 - CMV serology, EUC, LFT, EBV serology, FBE, iron studies, Lymphocyte markers

Hepatomegaly 2 - AFP, Alpha 1 antitrypsin, amoebic serology, Ceruloplasmin, Copper, Free light chains, fasting glucose, Hydatid serology, Immunofixation + Electrophoresis, Q fever serology

Hepatomegaly Autoimmune 2 - ANA, ANCA, mitochondrial Abs, smooth muscle Abs

Hypercalcaemia Adult 1 - ACE, Calcium, Albumin, Phosphate, PTH, TSH(+/- FT4 if TSH abnormal), EUC, Vit D

Hypercalcaemia Child 1 - ACE, Calcium, Albumin, Phosphate, PTH, TSH(+/- FT4 if TSH abnormal), EUC, Vit D

Hyperkalaemia 1 - Coombs direct, Cortisol 0800, EUC, LFT, FBE, fasting glucose, Haptoglobin, Short Synacthen test

Hyperlipidaemia 1 - EUC, LFT, GGT, fasting lipids, LDL, HDL, TSH(+/- FT4 if TSH abnormal)

Hyperatraemia - Osmolality, urine osmolality, EUC

Hypertension 1 - EUC, LFT, FBE, fasting lipids, LDL, HDL, urine microalbumin, TSH(+/- FT4 if TSH abnormal), Vit D

Hypertension 2 - Aldosterone, Dexamethasone suppression - overnight, 24 hour urine metanephrines, plasme metanephrines, Renin

Hypocalcaemia 1 - Calcium, Albumin, Phosphate, Calcium, Magnesium, PTH, EUC, Vit D

Hypogonadism male 1 - Chromosome cytogenetics, LH, Prolactin, Testosterone

Hypokalaemia 1 - EUC, LFT, urine potassium

Hyponatraemia 1 - fasting glucose, osmalality, urine osmalality, TSH(+/- FT4 if TSH abnormal, EUC

Hypothyroidism 1 - TFT, Thyroid Abs

Immunodeficiency 1 - C3, C4, ESR, FBE, fasting glucose, IgA, IgM, IgG, immunofixation + Electrophoresis, Protein electrophoresis

Immunodeficiency 2 - HIV, IgG, Immunofixation + Urine Electrophoresis, Lymphocyte markers, urine protein electrophoresis

Impotence 1 - FBE, FSH, fasting glucose, LFT, LH, SHBG, Testosterone

Infertility female 1 - FSH, LH, anti-Mullerian hormone, oestradiol, progresterone, prolactin, TFT

Infertility female 2 - 17-OH progresterone, cervical swab Chlamydial and Gonorrhoeal PCR, Chromosome cytogenetics, 24 hour urine cortisol, SHBG, Sperm Abs, Testosterone

Infertility male 1 - SHBG, Testosterone, LH, FSH, semen analysis

Infertility male 2 - Chromosome cytogenetics, Cystic fibrosis CTFR gene

Inflammatory Bowel Disease 1 - ANCA, ASCA  Abs, CRP, ESR, FBE, iron studies, stool MCS, parasites, Faecal multiplex PCR, Faecal calciprotein

IVF Female GP visit 1 Day 2-5 of cycle - FBE, iron studies, Anti Mullerian hormone, FSH, LH, Oestradiol, Prolactin, Rubella serology, SHBG, Syphillis serology, Testosterone, TSH(+/- FT4 if TSH abnormal), Chickenpox serology

IVF Female GP visit 2 Luteal Phase Day 21 - Oestradiol, Blood group and antibodies, Urine Chlamydial and gonorrhoeal PCR, fasting glucose, Hb electrophoresis, Hepatitis B serology, Hepatitis C serology, HIV, Insulin, Progresterone

IVF Male GP visit 1 - Semen analysis

IVF Male GP visit 2 - Urine Chlamydial and Gonorrhoeal PCR, Hepatitis B serology, Hepatitis C serology, HIV, Syphillis serology

Lymphadenopathy 1 - HIV, CMV serology, EBV serology, FBE, Rubella serology, ESR, Toxoplasmosis serology

Lymphadenopathy 2 - ACE, AFB MCS, ANA, Bartonella (cat scratch) serology, Lymphocyte markers

Malabsorption 1 - EUC, LFT, FBE, Gliadin Abs, IgA, Stool MCS, parasite, Faecal multiplex PCR, TSH(+/- FT4 if TSH abnormal), TTG Abs

Malabsorption 2 - Beta Carotene, Folate, Vit A, Vit B12, Vit D

Menorrhagia 1 - FBE, iron studies, Progresterone, TSH(+/- FT4 if TSH abnormal)

Miscarriage Recurrent 1 - ANA, Cardiolipin Abs, ENA, fasting glucose, Beta 2 glycoprotein Abs, TFT, Thyroid Abs

Miscarriage Recurrent 2 - Urine Chlamydial and gonorrhoeal PCR,Chromosome cytogenetics, Factor V Leiden genotype, Lupus anticoagulant, Protrombin genotype, Syphillis serology

Monoclonal Gammopathy 1 - Calcium, EUC, LFT,  ESR, FBE, Free light chains, IgA, IgG, IgM, Immunofixation + Electrophoresis, Immunofixation + Electrophoresis urine

Muscle weakness 1 - Calcium, EUC, LFT, Acetylcholine receptor Abs, CK, 24hour urine cortisol, CRP, TSH(+/- FT4 if TSH abnormal)

Myeloma 1 - Calcium, EUC, LFT, CRP, ESR, FBE, Free light chains, IgG, IgM, IgA, Immunofixation + Electrophoresis, Immunofixation + Electrophoresis urine, Beta2 microglobulin

Myositis 1 - CRP, ESR, FBE, CK

Myositis autoimmune suspected 2 - Acetylcholine receptor Abs, ANA, ANCA, ENA, muscle specific kinase Abs

Myositis infectious suspected 2 - Dengue serology, Leptospira serology, Toxoplasma serology

Neurology axonal suspected 1 - ANA, ANCA, ENA, HIV, Rheumatoid factor

Neurology axonal suspected 2 - Free light chains, Urine heavy metals, Immunofixation + Electrophoresis, Lead, PBG urine, Protein electrophoresis

Neuropathy peripheral first line 1 - EUC, LFT, ESR, FBE, fasting glucose, Syphillis serology, TSH(+/- FT4 if TSH abnormal), Vit B12

Organic brain dementia 1 - EUC, LFT, FBE, Syphillis serology, Vit B12, folate, HIV, TFT, urine MCS

Osteoporosis management 1 - Calcium, Albumin, Phosphate, C-telopeptide, Mg, P1NP, PTH, Vit D

Osteoporosis seconday cause female 1 - Vit D, 24 hour urine cortisol, EUC, LFT, ESR, FBE, Free light chains, Gliadin Abs,  Immunofixation + Electrophoresis, Protein electrophoresis, TSH(+/- FT4 if TSH abnormal),TTG Abs

Osteoporosis seconday cause male 1 - Vit D, 24 hour urine cortisol, EUC, LFT, ESR, FBE, Free light chains, Gliadin Abs,  Immunofixation + Electrophoresis, Protein electrophoresis, TSH(+/- FT4 if TSH abnormal),TTG Abs, testosterone

Ovarian malignancy 1 - EUC, LFT, FBE, AFP, CA 125, Calcium, BHCG, HE4/ROMA

Pancreatic malignancy 1 - CA 19-9, CEA, LFT

Pancreatitis acute 1 - Calcium, Albumin, Phosphate, CRP, EUC, LFT, FBE, Lipase

Penis discharge 1 - Urine Chlamydial and gonorrhoeal PCR, Swab MCS, Urine Trichomonas PCR, Urethral trichomonas PCR

Pharyngitis 1 - Throat Chlamydial and gonorrhoeal PCR, EBV serology, FBE, Swab MCS, Streptococcal serology

Pneumonia 1 - Blood culture, Legionella serology, Legionella urinary Ag, M.pneumonia serology, sputum MCS, Chlamydial serology, RSV PCR, Respiratory viral swab PCR, S.pneumonia urinary Ag

Polycystic Ovarian Syndrome Dx 1 - Androstenedione, DHEAS, FSH, BHCG, LH, Oestradiol, Prolactin, SHBG, Testosterone, TFT

Polycystic Ovarian Syndrome Management 1 - fasting glucose, lipids, LDL, HDL, LFT

Polycythaemia 1 - Erythropoetin, JAK2

Polyuria 1 - fasting glucose, urine MCS, EUC

Polyuria 2 - Osmolality, H₂O deprivation test

PUO Autoimmune Cause Suspected 1 - ANA, ANCA, Rheumatoid factior

PUO First Line 1 - Blood culture, CRP, ESR, EUC, LFT, FBE, urine MCS

PUO Haematology Malignancy Suspected 1 - FBE, Free light chains, Immunofixation + Electrophoresis, Lymphocyte markers, Protein Electrophoresis

PUO Infection Cause Suspected 1 - AFB MCS sputum, EBV serology, HIV, Streptococcal serology, Syphillis serology

PUO Infection Cause Suspected 2 - ACE, Brucella serology, CMV serology, Leptospira serology, M.pneumonia serology, Q fever serology, Rickettsia serology, Toxoplasma serology

PUO Infection Cause Suspected 3 - Dengue serology, Malaria parasites

Purpura/Bleeding 1 - Coags, ESR, Factor VIII, FBE, vWF

Renal Disease 1 - FBE, EUC, LFT, C3, C4, serum electrophoresis, ANCA, ENA, anti glomerular basement membrane antibodies, HBsAg, anti-HBc, anti-HBs, Hepatitis C serology, ANA, CRP, ESR, Calcium, Phosphate, Urine MCS, Urine Microalbumin

Renal Disease 2 - C3, C4, Free Light Chains, Immunofixation + Electrophoresis, Immunofixation + Electrophoresis urine, Streptococcal serology

Renal Disease 3 - C3, C4, ANCA, cryoglobulins, ENA, GMBA, Hepatitis B serology, Hepatitis C serology

Renal Disease 4 - AFB MCS Urine

Right Iliac Fossa Pain 1 - EUC, LFT, FBE, ESR, Urine MCS, BHCG

Sarcoidosis 1 - EUC, LFT, FBE, ACE, Calcium, Albumin, Phosphate

Splenomegaly 1 - ESR, FBE, ANA, ENA, LFT, Malaria parasites, Rheumatoid factor

STI Female 1 - Cervical Swab Chlamydial and Gonorrhoeal PCR, HBsAg, anti-HBc, anti-HBs, HIV, Swab MCS, Syphillis serology, Trichomonas Urine PCR, Trichomonas Swab PCR

STI Gay Male 1 - HBsAg, anti-HBc, anti-HBs, HIV, Syphillis serology, Urine Chlamydial and Gonorrhoeal PCR, Throat swab Chlamydial and Gonorrhoeal PCR, Rectal Swab Chlamydial and Gonorrhoeal PCR

STI Male 1 - HBsAg, anti-HBc, anti-HBs, HIV, Syphillis serology, Urethral Swab Chlamydial and Gonorrhoeal PCR, Swab MCS

STD test - HBsAg, anti-HBc, anti-HBs, Hepatitis C serology, HIV, Syphillis serology, Urine Chlamydial and gonorrhoeal PCR, Urine mycoplasma genitalium PCR

Tall Stature 1 - Growth Hormone, GTT, fasting glucose, IGF-1

Testicular Malignancy 1 - AFP, Calcium, Magnesium, Phosphate, EUC, LFT, BHCG,  Lactate Dehydrogenase

Thrombocytopenia 1 - ANA, Coags, Coombs Direct, D-dimer, FBE, Folate, Haptoglobin, Lupus anticoagulant, Reticulocyte count, Vit B12

Thrombocytosis 1 - Vit B12, ESR, Iron Studies, FOBT

Thrombophilia 1 - Coags, Factor V Leiden, FBE, Protrombin genotyping

Thrombophilia 2 - ANA, ATIII, Cardiolipin Abs, Lupus anticoagulant, Protein C, Protein S, Beta2 glycoprotein 1 Abs

Thyroiditis Hashimotos 1 - TFT, Thyroid Abs

Vaginal Discharge 1 - Cervical Swab Chlamydial and Gonorrhoeal PCR, Swab MCS, Urine Trichomonas PCR, Vaginal Swab Trichomonas PCR

Weight Gain 1 - 24 hour urine cortisol, fasting glucose, Fasting Lipids, LDL, HDL, TSH(+/- FT4 if TSH abnormal)

Weight Loss 1 - fasting glucose, TSH(+/- FT4 if TSH abnormal), Cortisol 0800, EUC, LFT, ESR, FBE